LEGAL NOTICE

The contents of the Aptose Biosciences, Inc. (“the Company”) web site are provided for informational and educational purposes only. All information is provided “as is” without any warranties of any kind and the Company makes no representation and disclaims all express and implied warranties and conditions of any kind, including without limitation, representations, warranties or conditions regarding accuracy, timeliness, completeness, non-infringement, merchantability or fitness for any particular purpose and Aptose Biosciences, Inc. assumes no responsibility to you or any third party for the consequences of any errors or omissions.

Aptose does not currently have any products approved for sale. Aptose can not assure when, if ever, any of its product candidates will be approved for sale in any jurisdiction.

Except for historical information, the information provided on this site contains forward-looking statements which reflect the Company’s current expectation regarding future events. These forward-looking statements involve risks and uncertainties which may cause actual results to differ materially from those statements. Those risks and uncertainties include, but are not limited to, the ability to obtain sufficient capital to fund research and development activities, changing market conditions, the successful and timely completion of clinical studies, the establishment of corporate alliances, the impact of competitive products and pricing, new product development, uncertainties related to the regulatory approval process, and other risks detailed from time-to-time in the Company’s ongoing quarterly filings, annual filing documents and other disclosures. Please go to SEDAR at www.sedar.com for our latest disclosure materials. For SEDAR filings prior to July 10, 2007 you will find these under the company profile for Global Summit Real Estate Inc.

Neither Aptose Biosciences, Inc. nor any of its officers, directors, employees or agents makes or has made any recommendation regarding the advisability of investing in the Company’s securities generally for any particular individual. Information disclosed under the corporate and securities laws of those jurisdictions applicable to the Company is not intended to be in any way qualified, amended, modified or supplemented by the information available in, through, or on this web site. Due to the technical and security risks inherent on the Internet and because the documents you may access may differ from the original depending on your browser software, the information accessed on this web site should not be used for the purpose of making investment decisions. Aptose Biosciences, Inc. shall not be liable to you and/or any third party for any damages of any kind arising out of or relating to the use of this web site including, but not limited to, any lost profits, lost opportunities, special, incidental, indirect, consequential or punitive damages, even if the Company is advised of such possibility.

The Company provides links to third party web sites only as a convenience and does not control such web sites, and is therefore not responsible for the content of any such web site. The inclusion of any link by the Company does not imply the endorsement, investigation or verification by the Company of the linked web site or the material contained therein.

All materials on this web site are protected by copyright. One copy can be downloaded for personal, non-commercial use provided all copyright and proprietary notices are kept intact and the material is not modified. All other rights are reserved. Trademarks or service marks of the Company include: Virulizin®. The information posted on this web site was accurate at the time of posting, but may be superseded by subsequent disclosures For additional information relating to this notice and other legal matters, please contact us at ir@aptose.com

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