Exhibit 31.1
Certification Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
I, William G. Rice, certify that:
| 1. | I have reviewed this Amendment No. 2 to Annual Report on Form 10-K/A of Aptose Biosciences Inc.; and |
| 2. | Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report. |
Date: April 12, 2019
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/s/ William G. Rice, Ph.D. Name: William G. Rice, Ph.D. Title: President and Chief Executive Officer
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