Annual reports filed by certain Canadian issuers pursuant to Section 15(d) and Rule 15d-4

Note 5 - Property and Equipment - Equipment (Details)

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Note 5 - Property and Equipment - Equipment (Details) - USD ($)
$ in Thousands
Dec. 31, 2017
Dec. 31, 2016
Jan. 01, 2016
Statement Line Items [Line Items]      
Laboratory equipment $ 142 $ 213 $ 314
Laboratory Equipment [Member]      
Statement Line Items [Line Items]      
Laboratory equipment 79 113  
Computer equipment [member]      
Statement Line Items [Line Items]      
Laboratory equipment 16 9  
Computer software included in property and equipment [member]      
Statement Line Items [Line Items]      
Laboratory equipment 1 25  
Fixtures and fittings [member]      
Statement Line Items [Line Items]      
Laboratory equipment 16 23  
Leasehold improvements [member]      
Statement Line Items [Line Items]      
Laboratory equipment 30 43  
Gross carrying amount [member]      
Statement Line Items [Line Items]      
Laboratory equipment 404 391  
Gross carrying amount [member] | Laboratory Equipment [Member]      
Statement Line Items [Line Items]      
Laboratory equipment 173 173  
Gross carrying amount [member] | Computer equipment [member]      
Statement Line Items [Line Items]      
Laboratory equipment 47 34  
Gross carrying amount [member] | Computer software included in property and equipment [member]      
Statement Line Items [Line Items]      
Laboratory equipment 80 80  
Gross carrying amount [member] | Fixtures and fittings [member]      
Statement Line Items [Line Items]      
Laboratory equipment 35 35  
Gross carrying amount [member] | Leasehold improvements [member]      
Statement Line Items [Line Items]      
Laboratory equipment 69 69  
Accumulated depreciation and amortisation [member]      
Statement Line Items [Line Items]      
Laboratory equipment 262 178  
Accumulated depreciation and amortisation [member] | Laboratory Equipment [Member]      
Statement Line Items [Line Items]      
Laboratory equipment 94 60  
Accumulated depreciation and amortisation [member] | Computer equipment [member]      
Statement Line Items [Line Items]      
Laboratory equipment 31 25  
Accumulated depreciation and amortisation [member] | Computer software included in property and equipment [member]      
Statement Line Items [Line Items]      
Laboratory equipment 79 55  
Accumulated depreciation and amortisation [member] | Fixtures and fittings [member]      
Statement Line Items [Line Items]      
Laboratory equipment 19 12  
Accumulated depreciation and amortisation [member] | Leasehold improvements [member]      
Statement Line Items [Line Items]      
Laboratory equipment $ 39 $ 26