Note 12 - Stock-based Compensation - Share-based Payment Expense (Details) - USD ($) $ in Thousands |
12 Months Ended | |
|---|---|---|
Dec. 31, 2021 |
Dec. 31, 2020 |
|
| Share-based payment expense | $ 12,949 | $ 21,438 |
| Research and Development Expense [Member] | ||
| Share-based payment expense | 3,789 | 3,720 |
| General and Administrative Expense [Member] | ||
| Share-based payment expense | $ 9,160 | $ 17,718 |
| X | ||||||||||
- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
|
| X | ||||||||||
- Details
|
| X | ||||||||||
- Details
|